Xeomin vs. Botox: Which is Better for You?

Have you ever dreaded the sight of yourself in the mirror? Tired of watching your once youthful look fade away? Time flies, and unfortunately, years of life experience show up on your face faster than other body parts, especially if you’re a facial expressive person. Crow’s feet, forehead wrinkles and frown lines is a natural part of aging, even with a good skincare routine and skin maintenance. Fortunately, there are aesthetic treatments available that can give you smoother skin, fewer lines and wrinkles, and a more youthful appearance. Injectable treatments like Xeomin and Botox can soften heavy lines and wrinkles and temporarily remove fine lines. Let’s take a look at the differences between Xeomin and Botox to help you decide which treatment is better for you to smooth out wrinkles and give you a more youthful and pleasant appearance.

What Are Xeomin and Botox?


Xeomin is manufactured by Merz Pharmaceuticals as an injectable medication that contains the active ingredient incobotulinumtoxinA. It is a type of botulinum toxin, similar to Botox (onabotulinumtoxinA) and Dysport (abobotulinumtoxinA). These medications are commonly used in medical and cosmetic procedures to temporarily reduce or eliminate wrinkles and fine lines by paralyzing or relaxing the muscles responsible for causing them. Unlike other forms of Botulinum toxin type A, the formulation of Xeomin does not contain the preservative protein that inhibits the body’s ability to produce antibodies against the neurotoxin, thus preventing it from becoming resistant over time.


Botox is a type of injectable wrinkle relaxer made by Allergan. It uses a special type of toxin called Onabotulin A to temporarily paralyze muscles, which helps reduce the appearance of wrinkles on your face. Botox was first approved by the FDA in 1989 for treating blepharospasms and other eye muscle issues. In 2002, it was approved for cosmetic use to reduce frown lines between your eyebrows. In 2013, the FDA approved Botox for treating wrinkles around your eyes’ corners (crow’s feet).

How do Xeomin and Botox Work?

Xeomin and Botox are both neuromodulators, which means they work by temporarily blocking the signals that nerves send to muscles. When these signals are blocked, the muscles relax, which can help to reduce the appearance of wrinkles and fine lines.

Xeomin for Frown Lines – 14 days before and after

What Makes Xeomin and Botox Different?

Xeomin and Botox are similar in many ways, as they both contain botulinum toxin type A and are used for cosmetic and medical purposes to reduce muscle activity. However, there are some key differences between the two products.


Xeomin is a highly purified form of botulinum toxin type A, while Botox contains other proteins in addition to the active ingredient. This difference in formulation may make Xeomin less likely to cause allergic reactions than Botox.

Protein Content

Botox is manufactured with a complexing protein, while Xeomin is manufactured without a complexing protein. The complexing protein in Botox is thought to help the product spread more evenly through the muscle tissue, but it may also increase the risk of side effects.

Onset and Duration

The effects of both Xeomin and Botox typically last for several months, but some studies have shown that Xeomin may last slightly longer.


Overall, Xeomin tends to be more economical than Botox at our medical spa locations in Austin, Temple, Lakeway and Pflugerville. You can even get $50 off your Xeomin treatment with our Xperience+ loyalty program. Prices for Xeomin are based on how many units of the injection you need for treatment or the areas you need treatment for. If you have any questions about costs, schedule a FREE consultation with our medical injectors to give you more details about what you can expect to spend and also potentially suggest ways to save.

What To Do After Your Xeomin or Botox Treatment?

For The Next 5 Hours

Do not touch, move or put any pressure on the treated area and stay as straight as you can.

For The Next 24 Hours

Avoid high, direct heat, including saunas, hot tubs, and steam rooms. Also, don’t do anything that puts a lot of strain on your body or raises your temperature, like lifting heavy objects or doing a lot of exercise.

For The Next 2 Weeks

Avoid facials, harsh scrubs, massages, or harsh exfoliation of the treatment area.

What To Do If You Have These Common Side Effects After Treatment?

Small Bumps

Nodules may develop at the site of the injection. These will dissipate when the medication is metabolized naturally (typically within 30 minutes). During this time, it is advised to avoid massaging the area.

Mild Headaches

A dull headache may occur after a few injections. They usually disappear within 36 hours. You can use over-the-counter pain relievers to relieve discomfort, but avoid aspirin.

Swelling or Discomfort

After multiple injections, some patients may experience mild discomfort. To prevent swelling and discomfort, place a cool ice pack on the affected area and take it off every 3 to 5 minutes for 1 to 2 hours. Do not put the ice pack directly on the skin. Do not take the ice pack off more than 5 minutes in a row.


Bruises can happen at any time after injections. Most bruises go away within 3 to 7 days. Makeup can be applied on the bruises gently. Avoid alcohol for as long as possible.


Itching can also happen when alcohol prep pads are applied to the skin. To reduce itching, take an oral antihistamine (like Benadryl or Allegra) and apply it to the affected area 3 times a day until it stops itching. You can also use hydrocortizone 1% and apply it to your skin, Vaseline, or Aquaphor.

How Do I Get Started With Xeomin Treatment at Medical Spa in Texas?

Do you want to get rid of wrinkles and look younger and more attractive today? Book an appointment for a Xeomin treatment at our Texas medical spa or schedule a free consultation with our medical injectors. We are dedicated to providing our patients with the best possible care, and we look forward to hearing from you!

Contact us at (512) 316-5259 or email@wishmedicalspa.com to schedule your consultation.

Disclaimer: Individual results may vary. Consult our experienced medical injectors to tailor the ideal treatment plan for your unique requirements.